P-098 Serious Infections in Patients Treated with Certolizumab Pegol with or Without Corticosteroids
نویسندگان
چکیده
منابع مشابه
Opportunistic infections in patients with temporal arteritis treated with corticosteroids.
emporal arteritis and polymyalgia rheumatica, different T clinical manifestations of the same systemic granulomatous vasculitis, predominantly affect older persons.' Huston and colleagues estimated the prevalence to be 1 in 750 persons older than 50 years of age.' Temporal arteritis often requires high and sometimes sustained corticosteroid therapy to prevent the development of sight threatenin...
متن کاملEffect of certolizumab pegol over 96 weeks in patients with psoriatic arthritis with and without prior antitumour necrosis factor exposure
OBJECTIVE Previous reports of RAPID-PsA (NCT01087788) demonstrated efficacy and safety of certolizumab pegol (CZP) over 24 weeks in patients with psoriatic arthritis (PsA), including patients with prior antitumour necrosis factor (TNF) therapy. We report efficacy and safety data from a 96-week data cut of RAPID-PsA. METHODS RAPID-PsA was placebo-controlled to week 24, dose-blind to week 48 an...
متن کاملthe past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
Certolizumab pegol for rheumatoid arthritis: effective in combination with methotrexate or as monotherapy
Rheumatoid arthritis (RA) is estimated to affect 5 million people worldwide [1] with 0.3–1% of the population in industrialized countries suffering from RA [2]. The development of RA is associated with increasing age and female gender, with the prevalence among women being approximately two-times greater than in men [3]. Although the etiology of RA remains unclear, the inflammation and joint da...
متن کاملSimultaneous Exposure–Response Modeling of ACR20, ACR50, and ACR70 Improvement Scores in Rheumatoid Arthritis Patients Treated With Certolizumab Pegol
The Markovian approach has been proposed to model American College of Rheumatology's (ACR) response (ACR20, ACR50, or ACR70) reported in rheumatoid arthritis clinical trials to account for the dependency of the scores over time. However, dichotomizing the composite ACR assessment discards much information. Here, we propose a new approach for modeling together the three thresholds: a continuous-...
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ژورنال
عنوان ژورنال: Inflammatory Bowel Diseases
سال: 2016
ISSN: 1078-0998
DOI: 10.1097/01.mib.0000480203.44901.5d